{"id":14182,"date":"2023-01-24T10:52:43","date_gmt":"2023-01-24T09:52:43","guid":{"rendered":"https:\/\/www.physiotutors.com\/?post_type=condition&#038;p=14182"},"modified":"2026-08-13T13:22:04","modified_gmt":"2026-08-13T11:22:04","slug":"cuboid-syndrome","status":"publish","type":"condition","link":"https:\/\/www.physiotutors.com\/conditions\/cuboid-syndrome\/","title":{"rendered":"Cuboid Syndrome"},"featured_media":14183,"template":"","tracking_tag":[2198,2313],"class_list":["post-14182","condition","type-condition","status-publish","has-post-thumbnail","hentry","tracking_tag-ankle-foot","tracking_tag-lower-extremity"],"acf":{"sections":[{"acf_fc_layout":"page-header-detail-page","background":{"background_image":14183,"background_image_alt_text":"Cuboid Syndrome"},"heading":"Cuboid Syndrome after lateral ankle sprain | Diagnosis & Treatment","subheading":"Ankle\/Foot","content_editor":"","button_type":"url","button_label":"","button_style":"button-five","button_internal_link":4646,"button_anchor":"","button_url":"https:\/\/www.physiotutors.com\/products\/the-manual-therapy-app\/","button_file":"","label":""},{"acf_fc_layout":"submenu","links":[{"button_type":"anchor","button_label":"Introduction & Pathomechanism","button_internal_link":null,"button_anchor":"section-number-3","button_url":"","button_file":null},{"button_type":"anchor","button_label":"Clinical Picture & Examination","button_internal_link":null,"button_anchor":"section-number-4","button_url":"","button_file":null},{"button_type":"anchor","button_label":"Treatment","button_internal_link":null,"button_anchor":"section-number-5","button_url":"","button_file":null},{"button_type":"anchor","button_label":"Manual Therapy App","button_internal_link":null,"button_anchor":"section-number-4","button_url":"","button_file":null},{"button_type":"anchor","button_label":"Reviews","button_internal_link":null,"button_anchor":"section-number-5","button_url":"","button_file":null}],"dropdown_label":"Go to","button_right":{"button_type":"internal_link","button_label":"Become a member","button_style":"button-three","button_internal_link":22104,"button_anchor":"","button_url":"","button_file":""},"button_description":""},{"acf_fc_layout":"content-with-sidebar","content_editor":"<h2>Cuboid Syndrome after lateral ankle sprain | Diagnosis &amp; Treatment<\/h2>\r\nCuboid syndrome has also been referred to in the literature as subluxed cuboid, locked cuboid, dropped cuboid, cuboid fault syndrome, lateral plantar neuritis, and peroneal cuboid syndrome (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24357955\/\" target=\"_blank\" rel=\"noopener\">Patterson et al. 2006<\/a>)\r\n<div class=\"embed-container\">\r\n\r\nAnkle sprains account for a big portion of lower extremity injuries with up to 40% of cases having residual symptoms.\u00a0There is a hypothesis that the cuboid may be responsible for those cases in which lateral ankle pain persists. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27442099\/\" target=\"_blank\" rel=\"noopener\">Newell et al. (1981)<\/a> report that 4% of all athletes with foot problems present with cuboid syndrome.\u00a0 It appears that the condition has a higher prevalence in professional ballet dancers with up to 17% of reported foot and ankle injuries (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/1558245\/\" target=\"_blank\" rel=\"noopener\">Marshall et al. 1992<\/a>).\r\n<div class=\"embed-container\">\r\n\r\n[embed]https:\/\/www.youtube.com\/watch?v=eXw36a52avo[\/embed]\r\n\r\n<\/div>\r\n<\/div>\r\n&nbsp;\r\n<h3><strong>Pathomechanism<\/strong><\/h3>\r\nThe hypothesis for cuboid syndrome is based on history, clusters of signs and symptoms, differential diagnosis, clinical expertise, and of course mechanism of injury.\u00a0 It\u2019s assumed that during a severe initial inversion trauma, torsion between the cuboid and navicular bone and cuneiform as well as the calcaneus leaves the cuboid in a relatively supinated position.<img class=\"alignnone size-full wp-image-14183\" src=\"https:\/\/www.physiotutors.com\/wp-content\/uploads\/2023\/01\/Cuboid-Syndrome.jpg\" alt=\"Cuboid syndrome\" width=\"1138\" height=\"655\" \/>"},{"acf_fc_layout":"content-with-sidebar","content_editor":"<h3>Clinical Picture &amp; Examination<\/h3>\r\n<div class=\"embed-container\"><\/div>\r\nThis disposition remains painful, specifically over the calcaneocuboid joint, while tenderness over lateral ankle ligaments subsides.\r\nPatients display antalgic gait with an increase in pain during the push-off phase and If pain allows for mobility testing, joint play is absent.\r\n\r\n&nbsp;\r\n\r\n<em><strong>Examination<\/strong><\/em>\r\n\r\nAs previously mentioned differential diagnosis is necessary and the first step in assessing ankle sprains should be to exclude a fracture by using the <a href=\"https:\/\/www.physiotutors.com\/wiki\/ottawa-ankle-rules\/\">Ottawa Ankle rules<\/a>.\r\nMidtarsal mobility testing in supination and adduction may reproduce the patient's symptoms. According to <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16108581\/\" target=\"_blank\" rel=\"noopener\">Jennings et al. (2005)<\/a>, pronation and abduction may also elicit pain occasionally. The cuboid is unique as it is the only bone in the foot that articulates with both the tarsometatarsal joint (Lisfranc complex) and the midtarsal joint (Chopart\u2019s Joint), and is the only bone linking the lateral column to the transverse plantar arch (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24357955\/\" target=\"_blank\" rel=\"noopener\">Patterson et al. 2006<\/a>). Therefore, it makes sense to assess both the Line of Lisfranc and the Line of Chopart during mobility testing.\r\n<div class=\"embed-container\">\r\n\r\n[embed] https:\/\/www.youtube.com\/watch?v=0ugLq8Ns5VU[\/embed]\r\n\r\n<\/div>\r\nFurthermore, the same authors recommend performing additional functional testing in the form of heel\/toe raises or single-leg hopping. These activities are commonly difficult or impossible to perform due to pain.\r\nUnfortunately, radiological evaluation does not seem to have added value in the diagnosis of Cuboid syndrome (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7987383\/\" target=\"_blank\" rel=\"noopener\">Mooney et al. 1994<\/a>).\r\n\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16108581\/\" target=\"_blank\" rel=\"noopener\">Jennings et al. (2005)<\/a> summarize the clinical findings as follows:\r\n\r\n<strong><em>Subjective findings<\/em><\/strong>\r\n<ul>\r\n \t<li>Mechanism of injury (plantar flexion\/inversion)<\/li>\r\n \t<li>Pain location (lateral midfoot\/ankle)<\/li>\r\n<\/ul>\r\n<em><strong>Objective findings<\/strong><\/em>\r\n<ul>\r\n \t<li>Pain on palpation of the cuboid<\/li>\r\n \t<li>Positive midtarsal mobility testing (symptom reproduction)<\/li>\r\n \t<li>Positive dorsal\/plantar and\/or plantar\/dorsal mobility testing(pain)<\/li>\r\n \t<li>Antalgic gait (most prominent during the push-off phase)<\/li>\r\n \t<li>Manual muscle tests\u2014resisted inversion\/eversion (pain and possible weakness)<\/li>\r\n \t<li>Functional testing (heel\/toe raises or single leg hop testing)Differential diagnoses<\/li>\r\n \t<li>Radiological\/imaging studies to rule out other pathologies<\/li>\r\n<\/ul>\r\n[cta]"},{"acf_fc_layout":"content-with-sidebar","content_editor":"<h3><strong>Treatment<\/strong><\/h3>\r\nA technique that\u2019s described in the literature is the reposition manipulation into relative pronation. It\u2019s reported that following the manipulation, patients were pain-free the following day and could return to their activity.\r\n\r\n<em><strong>Reposition manipulation<\/strong><\/em>\r\n\r\nThe patient lies supine with the legs extended and the foot hanging over the edge of the bench.\r\nYou\u2019re going to stand medially to the foot and place hypothenar of your heteronymous hand on the lateral and plantar aspect of the cuboid just proximal to the base of the fifth metatarsal.\r\nThe hypothenar of the other hand is placed dorsally and medially on the cuboid which is lateral and proximal to the line between the third and fourth digit.\r\nIn this position, the forearms form a straight line. After you fold your hands together, the patient makes an active maximal dorsiflexion which pre-tensions the cuboid in submaximal eversion.\r\nBuild up compression through your elbows as well as increase the pre-tension in pronation direction.\r\nAsk the patient to relax the foot and perform a pronation swing with both elbows combined with a compression impulse of both hypothenars.\r\nThen slowly let go of the foot.\r\n\r\n<em><strong>Cuboid whip manipulation<\/strong><\/em>\r\n\r\nAnother technique described by <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16108581\/\" target=\"_blank\" rel=\"noopener\">Jennings et al. (2005)<\/a> is the cuboid whip manipulation:\r\n\r\n[caption id=\"attachment_14184\" align=\"alignnone\" width=\"544\"]<img class=\"wp-image-14184 size-full\" src=\"https:\/\/www.physiotutors.com\/wp-content\/uploads\/2023\/01\/Cuboid-manipulation-A.jpg\" alt=\"Cuboid manipulation A\" width=\"544\" height=\"410\" \/> Image from Jennings et al. (2005)[\/caption]\r\n\r\n[caption id=\"attachment_14185\" align=\"alignnone\" width=\"556\"]<img class=\"wp-image-14185\" src=\"https:\/\/www.physiotutors.com\/wp-content\/uploads\/2023\/01\/Cuboid-manipulation-B.jpg\" alt=\"Cuboid manipulation b\" width=\"556\" height=\"411\" \/> Image from Jennings et al. (2005)[\/caption]\r\n\r\n[caption id=\"attachment_14186\" align=\"alignnone\" width=\"555\"]<img class=\"wp-image-14186 \" src=\"https:\/\/www.physiotutors.com\/wp-content\/uploads\/2023\/01\/Cuboid-manipulation-C.jpg\" alt=\"Cuboid manipulation c\" width=\"555\" height=\"418\" \/> Image from Jennings et al. (2005)[\/caption]\r\n\r\nThe cuboid manipulation is performed with the patient in the prone position, starting with the knee flexed to 70\u00b0 and the ankle near neutral (A). The knee is then passively extended as the ankle is plantar flexed with slight supination of the subtalar joint (B).A thrust force is applied using both thumbs on the plantar aspect of t he cuboid (C).\r\nThis technique is also illustrated in detail in our <a href=\"https:\/\/www.physiotutors.com\/products\/the-manual-therapy-app\/\">Manual Therapy App<\/a>.\r\n\r\nOther methods of conservative treatment including various therapeutic modalities, therapeutic exercise, low dye arch taping, and padding are adjuncts to the cuboid manipulation techniques (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24357955\/\" target=\"_blank\" rel=\"noopener\">Patterson et al. 2006<\/a>).\r\n\r\n&nbsp;\r\n\r\n&nbsp;\r\n<h3><strong>References<\/strong><\/h3>\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16108581\/\" target=\"_blank\" rel=\"noopener\">Jennings, J., &amp; Davies, G. J. (2005). Treatment of cuboid syndrome secondary to lateral ankle sprains: a case series.\u00a0Journal of orthopaedic &amp; sports physical therapy,\u00a035(7), 409-415.<\/a>\r\n\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/1558245\/\" target=\"_blank\" rel=\"noopener\">Marshall, P., &amp; Hamilton, W. G. (1992). Cuboid subluxation in ballet dancers.\u00a0The american journal of sports medicine,\u00a020(2), 169-175.<\/a>\r\n\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7987383\/\" target=\"_blank\" rel=\"noopener\">Mooney, M., &amp; Maffey-Ward, L. (1994). Cuboid plantar and dorsal subluxations: assessment and treatment.\u00a0Journal of Orthopaedic &amp; Sports Physical Therapy,\u00a020(4), 220-226.<\/a>\r\n\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27442099\/\" target=\"_blank\" rel=\"noopener\">Newell, S. G., &amp; Woodle, A. (1981). Cuboid syndrome.\u00a0The Physician and Sportsmedicine,\u00a09(4), 71-76.<\/a>\r\n\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24357955\/\" target=\"_blank\" rel=\"noopener\">Patterson, S. M. (2006). Cuboid syndrome: a review of the literature.\u00a0Journal of Sports Science &amp; Medicine,\u00a05(4), 597.<\/a>"},{"acf_fc_layout":"cta-special","heading":"150+ Mobilization and Manipulation Techniques in Your Pocket","subheading":"App","button_type":"internal_link","button_label":"Get our MT app","button_style":"button-link-one","button_internal_link":5066,"button_anchor":"","button_url":"","button_file":null,"image":{"image_image":8427,"image_image_alt_text":"Manual Therapy App"},"background":{"background_image":5490,"background_image_alt_text":""}},{"acf_fc_layout":"slider-reviews-wp-review-slider-pro","heading":"What customers have to say about the MT app","subheading":"Reviews","content":"[wprevpro_usetemplate tid=\"6\"]"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Cuboid Syndrome after lateral ankle sprain | Diagnosis &amp; Treatment<\/title>\n<meta name=\"description\" content=\"Cuboid Syndrome describes the displacement of the cuboid bone in supination after a lateral ankle sprain. 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